Chlorohydrin formation [Cl2/H2O]

Chlorohydrin formation [Cl2/H2O] Chlorohydrin Formation Definition: The chlorohydrin formation reaction involves adding chlorine and water to a double bond and creating a chlorohydrin (chloro=chlorine, hydrin=hydro, water/H2O). Chlorohydrin Formation Explained: When chlorination occurs in a non-nucleophilic solvent, such as CHCl3 or…

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Chlorination [Cl2 plus catalyst]

Chlorination [Cl2 plus catalyst] Chlorination [Cl2 plus catalyst] Definition: Treatment of an aromatic (such as benzene) with chlorine (Cl2) and a Lewis base such as AlCl3 or FeCl3 leads to the formation of the chlorinated aromatic by electrophilic aromatic substitution. Chlorination [Cl2 plus catalyst]…

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Sulfonylation [SO3/H2SO4]

Sulfonylation [SO3/H2SO4] Sulfonylation [SO3/H2SO4] Definition: Treatment of an aromatic molecule such as benzene with sulfur trioxide and strong acid leads to the formation of sulfonic acid in the reaction of electrophilic aromatic substitution. Sulfonylation [SO3/H2SO4] Explained: Concentrated sulfuric acid…

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Side chain bromination

Side chain bromination Side chain bromination Definition: When treated with N-bromosuccinimide (NBS) and light (hν) alkyl group adjacent to aromatic groups will be converted to into alkyl bromides. Side chain bromination Explained: This reaction is analogous to allylic…

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