Glycoside

Glycoside Definition:

An acetal that is obtained by treating the cyclic hemiacetal form of a monosaccharide with alcohol under acid-catalyzed conditions.

Glycoside Explained:

When a monosaccharide interacts with alcohol in the presence of an acid catalyst called glycosides. When the naming of glycosides, the (ose) suffix of the sugar name is replaced by (oside), and the alcohol group name is placed first. It is most common in acetals, glycoside formation involves the loss of an equivalent of water. The diether product is stable to the base and alkaline oxidants such as Tollen’s reagent. Since acid-catalyzed aldolization is reversible, glycosides may be hydrolyzed back to their alcohol and sugar components by aqueous acid.