Definition

For proteins, a feature of secondary structure that forms when two or more protein chains line up side-by-side.

Explanation

In this formation, hydrogen bonding occurs between the C=O and N-H groups. This type of formation usually occurs when the functional (R) side group are relatively small, because the larger functional group will block the necessary proximity required to achieve hydrogen bonding.

Structural reaction scheme for Beta (b) Pleated Sheet
Figure. Beta (b) Pleated Sheet