Hofmann Elimination

Hofmann Elimination Hofmann Elimination Definition: Tetra-alkyl ammonium salts undergo elimination to form the least substituted alkene. This is called the Hofmann elimination. Hofmann Elimination Explained: Amines, like alcohols, contain a poor leaving group which must be converted…

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E2 Alkenes from alkyl halides

E2: Alkenes from alkyl halides E2: Alkenes from alkyl halides Definition: Addition of a strong base to an alkyl halide results in elimination to form an alkene. E2: Alkenes from…

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E1 with rearrangement [hydride shift]

E1 with rearrangement [hydride shift] E1 with rearrangement [hydride shift] Definition: When unstable carbocations are formed under conditions typical for E1 reactions, hydride shift can occur. E1 with rearrangement [hydride…

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E1: Alkenes from alkyl halides

E1: Alkenes from alkyl halides E1: Alkenes from alkyl halides Definition: Alkyl halides that can readily form carbocations will undergo elimination to form alkenes. E1: Alkenes from alkyl halides Explained:…

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Alkenes from alcohols [strong acid]

Alkenes from alcohols [strong acid] Alkenes from alcohols [strong acid] Definition: Addition of acid to alcohols can result in elimination to form the corresponding alkene along with a molecule of…

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Alkenes from alcohols [POCl3]

Alkenes from alcohols [POCl3] Alkenes from alcohols [POCl3] Definition: When treated with phosphorus oxychloride (POCl3) alcohols are converted to alkenes via an elimination reaction. Alkenes from alcohols [POCl3] Explained: As we know, hydroxide (OH‾) is a…

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E1 vs. E2

Table of Contents For E1 reaction For E2 reaction The Zaitsev Rule With E1 and E2 mechanisms we have already met, but let’s compare them now. Both are elimination reactions. When alkyl halides react…

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