Ethers & Epoxides

7 reactions in this topic, each with the reagents, the mechanism and the structure of the product.

Epoxidation is treatment where an electrophilic oxidizing agent is capable of introducing a single oxygen atom to connect to both

Epoxides or oxacyclopropanes can be obtained by reaction so-called epoxidation from alkenes with peroxy acids.

Halohydrins treated with strong base (such as hydroxide anion) can form epoxides through with intramolecular SN2 reaction.

When acid is added to epoxides, nucleophiles will add to the more substitution position. The stereochemistry of this addition is t

When epoxides are treated with negatively charged nucleophiles, they will add to the least substituted position of epoxide in an S

When aqueous acid is added to epoxide, trans-diol are formed.

The Sharpless Epoxidation (or SAE, Sharpless Asymmetric Epoxidation) is an enantioselective epoxidation of allylic alcohols. Let’s