Rearrangements & Named Reactions

12 reactions in this topic, each with the reagents, the mechanism and the structure of the product.

Treatment of tertiary alcohols with HBr leads to the formation of tertiary alkyl bromides.

The Diels-Alder reaction converts a diene and an alkene (usually electron-poor, called a “dienophile”) into a six-membered ring co

The Hell-Volhardt-Zelinsky [HVZ] reaction is a means of converting a carboxylic acid to a brominated carboxylic acid (the bromine

The Kiliani-Fischer synthesis is a method by which we can lengthen the carbon chain on a sugar molecule by adding an additional ca

The Malonic ester synthesis is a method for making substituted carboxylic acids. It is a combination of four reactions:

The Mannich reaction is an organic reaction used to convert a primary or secondary amine and two carbonyl compounds (one non-enoli

Treatment of vicinal (or 1,2-) diols with an oxidant such as NaIO4, HIO4, or Pb(OAc)4 cleaves carbon-carbon bonds and forms carbon

The Pinacol Rearrangement involves the shift of an alkyl group accompanied by loss of water and the conversion of an alcohol to a

Thioacetals can be desulfurized to give alkanes through the use of the Raney nickel (Ra-Ni).

The Robinson Annulation is a method for forming the six-membered ring. It is a sequential combination of the Michael addition and

The Stork enamine reaction is a method for alkylation or acylation of ketones through intermediates enamines.

Treatment of an acid halide with diazomethane (CH2N2) followed by heating leads to the formation of a ketene which can be further