Aryne Formation (SNAr via arynes)
Aryne or benzyne is an intermediate that is obtained when treated halobenzene and strong base via an elimination-addition mechanis
13 reactions in this topic, each with the reagents, the mechanism and the structure of the product.
Aryne or benzyne is an intermediate that is obtained when treated halobenzene and strong base via an elimination-addition mechanis
Treatment with an aromatic such as benzene with bromine (Br2) and a Lewis acid (such as AlCl3 or FeCl3) leads to formation the bro
Treatment of an aromatic (such as benzene) with chlorine (Cl2) and a Lewis base such as AlCl3 or FeCl3 leads to the formation of t
The chlorohydrin formation reaction involves adding chlorine and water to a double bond and creating a chlorohydrin (chloro=chlori
In Friedel-Crafts acylation, a benzene ring is treated with an acid chloride (RCOCl) and catalyst (AlCl3 or FeCl3) to form a keton
In Friedel-Crafts alkylation, treatment of benzene with an alkyl halide and a Lewis acid (AlCl3 or FeCl3) forms an alkylbenzene. T
Treatment of an aromatic such as benzene with iodine (I2) and copper (II) leads to the formation of the iodinated benzene by elect
Aromatic groups can be nitrated by the action of nitric acid and an acid catalyst in the reaction of electrophilic aromatic substi
Nucleophilic aromatic substitution is a reaction in which the aromatic ring is attacked by the nucleophile. For example, when an a
When treated with a metal catalyst such as palladium (Pd) or platinum (Pt) and hydrogen gas (H2) ketones next to aromatic groups a
Nitro groups can be converted into amino groups by treatment with reducing agents such as palladium on carbon with hydrogen (Pd/C,
When treated with N-bromosuccinimide (NBS) and light (hν) alkyl group adjacent to aromatic groups will be converted to into alkyl
Treatment of an aromatic molecule such as benzene with sulfur trioxide and strong acid leads to the formation of sulfonic acid in