Definition
Treatment of an aromatic such as benzene with iodine (I2) and copper (II) leads to the formation of the iodinated benzene by electrophilic aromatic substitution.
![Structural reaction scheme for Iodination [I2/catalyst], diagram 1 of 3](/media/Iodination1-768x429.png)
Explanation
Since iodine is unreactive toward aromatic rings, oxidizing agents such as CuCl2 are used as a catalyst. As well as in any electrophilic aromatic substitution the catalyst is activated first:
And then benzene makes a nucleophilic attack to electrophilic iodine to form sigma complex, or arenium ion, which is resonance stabilized. This cationic intermediate is temporary charged-delocalized which is but with subsequent fast deprotonation regenerates the (now substituted) aromatic ring.
![Structural reaction scheme for Iodination [I2/catalyst], diagram 2 of 3](/media/Iodination2-1.png)
![Structural reaction scheme for Iodination [I2/catalyst], diagram 3 of 3](/media/Iodination3-1024x403.png)